TABLE 5.

Multivariable models to predict regression to NGR in DPP participants

Variables	HR (95% CI)	P
Weighted GRS (per risk allele)	0.95 (0.93–0.98)	<0.0001
Metformin (vs. placebo)	1.26 (0.98–1.62)	0.08
Lifestyle (vs. placebo)	2.38 (1.89–2.99)	<0.0001
Female (vs. male)	0.81 (0.66–0.99)	0.04
African American (vs. white)	1.22 (0.95–1.58)	0.12
Hispanic (vs. white)	0.96 (0.74–1.24)	0.76
Asian/Pacific Islander (vs. white)	0.52 (0.31–0.84)	0.009
American Indian (vs. white)	1.16 (0.63–2.14)	0.64
Age at randomization (per year)	0.98 (0.97–0.99)	<0.0001
Waist circumference (per cm)	0.98 (0.98–0.99)	<0.0001