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Effect of chronic alcohol feeding on [3H]biotin uptake by rat renal brush-border membrane vesicles (BBMV). A and B: carrier-mediated uptake of [3H]biotin (0.25 μM) by kidney BBMV of rats fed an alcohol liquid diet for 2 and 4 wk, respectively, and their pair-fed controls as described in materials and methods was examined. Values are means ± SE of 6–9 separate uptake determinations from multiple sets of rats. *P < 0.01.
