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Hydrophobic and hydrogen bond interactions of BI 201335 with NS3-NS4A protease. a, 3.6-Å interaction surface colored by hydrophobic (green), mildly polar (blue), and H-bonding (purple). b, intermolecular hydrogen and halogen bond interactions are indicated by green and cyan lines, respectively. Select intramolecular hydrogen bonds are indicated by black dotted lines.
