TABLE 1.

Identification of nine miRNAs that are differentially up-regulated in db/db glomeruli and high glucose-treated kidney microvascular endothelial cells and cultured podocytes

The relative expression of the up-regulated miRNAs is shown. All data are expressed as the mean signal intensity. Log2 represents mean signal intensity of Group2/Group1. miRNAs are listed in the order of their log2 differences based on values obtained from kidney glomeruli (from high to low).

miRNA ID	Kidney glomeruli				Mouse kidney microvascular endothelial cells				Mouse cultured podocytes
	Group1 (db/m)	Group2 (db/db)	Log2	p	Group1 (NG)	Group2 (HG)	Log2	p	Group1 (NG)	Group2 (HG)	Log2	p
mmu-miR-192	361	1,902	2.40	0.002	90	190	2.40	0.004	133	492	1.88	0.050
mmu-miR-29c	395	1,693	2.10	0.002	67	693	3.37	0.005	292	417	0.51	0.049
mmu-miR-26b	168	387	1.21	0.005	1,132	1,914	0.76	0.003	4,826	8,336	0.79	0.042
mmu-miR-1196	189	318	0.75	0.016	162	411	1.35	0.001	282	793	1.49	0.000
mmu-miR-1195	165	266	0.69	0.004	286	741	1.38	0.006	580	750	0.37	0.032
mmu-miR-200b	142	217	0.61	0.015	95	503	2.40	0.005	1,871	3,756	1.01	0.007
mmu-let-7g	1,235	1,890	0.61	0.007	2,162	3,269	0.60	0.010	935	2,071	1.15	0.023
mmu-miR-200a	182	265	0.54	0.016	212	547	1.37	0.027	322	990	1.62	0.017
mmu-miR-705	557	716	0.36	0.013	243	336	0.47	0.006	11,928	20,979	0.81	0.001