Table 1.
Blood Flow, Hz |
Vascular Conductance, Hz/mmHg |
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Experimental Procedure | n | Mean Arterial Pressure, mmHg | Heart Rate, beats/min | Iliac | Mesenteric | Renal | Iliac | Mesenteric | Renal |
Intact | 8 | 91.4 ± 4.0 | 323.5 ± 9.4 | 826.6 ± 63.1†‡ | 1,228.4 ± 72.3 | 1,771.9 ± 213.7 | 9.3 ± 1.0†‡ | 13.7 ± 1.2 | 19.3 ± 2.2 |
ADX | 8 | 82.3 ± 1.8 | 336.1 ± 16.3 | 834.4 ± 68.7†‡ | 1,344.0 ± 169.7§ | 2,283.6 ± 215.2 | 10.3 ± 0.9†‡ | 16.4 ± 2.0§ | 27.8 ± 2.5* |
ßX | 7 | 92.1 ± 3.8 | 300.0 ± 7.5 | 697.0 ± 71.3‡ | 1,424.8 ± 138.8 | 1,761.4 ± 307.3 | 7.6 ± 0.7‡ | 15.5 ± 1.3 | 19.3 ± 3.6 |
VX | 7 | 81.2 ± 2.6 | 351.7 ± 22.3 | 997.0 ± 194.4‡ | 1,184.6 ± 129.8§ | 2,685.2 ± 123.5* | 12.5 ± 2.6‡ | 14.6 ± 1.5§ | 33.1 ± 1.3* |
SAD | 7 | 86.1 ± 5.7 | 386.7 ± 16.3* | 732.4 ± 86.8‡ | 1,150.7 ± 163.7 | 1,609.9 ± 200.2 | 8.7 ± 1.2†‡ | 13.6 ± 1.9 | 18.7 ± 2.1 |
ADX + VX | 8 | 76.5 ± 2.7* | 341.8 ± 10.1 | 1,554.6 ± 149.1* | 1,384.8 ± 154.4 | 1,550.9 ± 153.3 | 20.6 ± 2.2* | 18.6 ± 2.4 | 20.3 ± 1.9 |
SAD + ADX | 8 | 78.8 ± 2.3* | 414.4 ± 21.9* | 1,076.3 ± 192.2‡ | 969.1 ± 71.7*§ | 2,115.6 ± 231.5 | 13.7 ± 2.4‡ | 12.4 ± 1.0§ | 27.1 ± 3.2 |
Data are means ± SE; n, no. of rats. Resting values for intact (INT) animals and following: bilateral adrenalectomy (ADX), β-adrenergic blockade (βX), vasopressin V1 receptor blockade (VX), adrenalectomy +V1 receptor blockade (ADX + VX), sinoaortic denervation (SAD), and sinaortic denervation + adrenalectomy (SAD + ADX).
P < 0.05 vs. intact.
P < 0.05, iliac vs. mesenteric (†), iliac vs. renal (‡), and mesenteric vs. renal (§).