Table 2.
Average maximum and steady-state hemodynamic responses evoked by β-adrenergic and V1 vasopressin receptor blockades
| Response | Experimental Procedure | n | ΔMAP, % | ΔHR, % | Δ Iliac, % | Δ Mesenteric Vascular Conductance, % | ΔRenal, % |
|---|---|---|---|---|---|---|---|
| Maximal | βX | 7 | 19.2 ± 4.0 | −8.6 ± 1.6 | −30.3 ± 4.2†‡ | −16.2 ± 4.0 | −13.0 ± 3.3 |
| VX | 8 | −16.6 ± 4.7 | 6.1 ± 4.0 | 38.4 ± 9.9 | 26.7 ± 6.3 | 25.9 ± 7.4 | |
| Steady state | βX | 7 | 5.9 ± 5.7 | −4.2 ± 1.8 | −11.7 ± 7.8†‡ | 6.4 ± 5.8 | 11.0 ± 6.7 |
| VX | 8 | −3.2 ± 3.6 | −2.9 ± 2.5 | 13.6 ± 8.9 | 7.6 ± 5.6 | 15.2 ± 10.3 |
Data are means ± SE; n, no. of rats. Δ, Change; MAP, mean arterial pressure; HR, heart rate. P < 0.05, iliac vs. mesenteric (†) and iliac vs. renal (‡). No significant differences between mesenteric vs. renal vascular beds were observed. All maximal responses, except for the increase in HR following VX, were significantly different from 0, whereas no steady-state responses were different from 0, except for the decrease in HR following βX.