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CTGF induced pulmonary hypertension. A: right ventricular systolic pressure (RVSP). B: weight ratio of right ventricle to left ventricle plus septum (RV/LV+S) in 2-wk-old control and CTGF mice. Overexpression of CTGF significantly increased RVSP and RV/LV+S. N = 6 in control group and 4 in CTGF group. **P < 0.001.
