Table 4.

Pre- and posttherapy IgM antibody titers and serologic analyses

Patient no.	Week no.	ELISA titers	FACS % of positive cells	MFI	CDC % lysis
1	2	0	10.8	92.6	3
	9	320	43.6	197.3	15.7
2	1	0	11	145.1	2.7
	5	80	10.8	146.5	9.1
3	1	10	10.4	65.2	−2.8
	13	320	64.7	154.4	37.3
4	1	0	10.2	61.5	4.7
	5	160	56.5	230.2	27.7
5	1	0	11.5	121.4	6.3
	5	320	30.2	210.0	30.6
6	1	0	11	152.9	3.2
	9	20	14.8	171.6	−3.4
7	1	0	10.5	136.4	8.8
	5	320	53.8	440.5	30.2
8	1	0	10.6	133.6	6.1
	7	10	10	109.1	6.3
9	1	0	11.1	115.1	2.5
	9	40	31.6	179.9	22.0
10	2	0	10	384.1	14.1
	9	0	33.3	333.1	11.6
11	1	0	10.3	204.2	13.2
	5	640	20.4	265.2	25.2
12	1	0	10.6	142.2	16.9
	5	80	57.6	413.0	25.7
13	1	0	9.4	52.1	0.4
	5	0	24	50	10.4
14	1	0	10.2	141	31.8
	9	40	29.8	270.7	48.3
15	1	0	9.7	27.4	0.4
	5	0	57.6	94.7	21.4
16	1	0	9.3	90.5	11.5
	5	80	36.5	170.8	9.7
17	1	0	9.9	166.9	56.3
	5	160	69.9	434.6	55.8
18	1	0	10.4	52.3	2.9
	5	0	71.1	168.2	0.7
19	1	0	9.9	70	6.1
	13	40	47.9	167.4	12.8
20	1	0	10.2	108.1	1.4
	5	40	58.2	476.5	35.7
21	1	0	9.8	83.1	13.9
	5	20	59	222.8	42.6
22	1	0	10	111.1	2.9
	9	40	56.8	309.4	11.5
23	1	0	9.8	71.8	4.9
	9	160	59.3	330.2	13.0
24	1	0	10.2	83.5	2.9
	5	80	43.7	218.1	17.9
25	1	0	9.8	99.0	24.8
	5	2560	67.6	512.1	58.0
26	1	0	10.2	76.9	5.3
	5	20	21.2	90.9	11.1
27	1	0	10.3	48.7	8.5
	9	10	10.3	26.9	16.2

MFI, mean fluorescence intensity. Bold numbers indicate a significant change.