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. 2010 Dec 24;300(3):H736–H744. doi: 10.1152/ajpheart.01024.2010

Fig. 2.

Fig. 2.

Confirmation of hypoxic status of animals. Hematocrit (A) and vascular endothelial growth factor (VEGF, B) protein levels increased in response to hypoxia treatment in both groups (n = 8–16 animals/group). C: representative Western blot for VEGF receptor (R) 2 levels. D: quantification of Western blot analysis showed that VEGF-R2 protein levels increased in the control animals in response to hypoxia and also increased in response to radiation (n = 6/group). E: representative Western blot for cortical hypoxia-inducible factor (HIF)-1α in nuclear fractions. F: quantification of the Western blot showed that, in the normoxic-treated radiated group, nuclear HIF-1α is increased compared with controls (n = 4/group). CN, control normoxia; CH, control hypoxia; RN, radiated normoxia; RH, radiated hypoxia. *P < 0.05 and ***P < 0.001 vs. the normoxic group. #P < 0.05 and ##P < 0.01 vs. the control normoxic group.