Table 2.
Experiment | Heart Rate, beats/min | Coronary Flow, ml/min | LV Developed Pressure, mmHg | Rate-Pressure Product, mmHg·beats·min−1 | dP/dtmax, mmHg/s | dP/dtmin, mmHg/s |
---|---|---|---|---|---|---|
1. Effect of differing edema toxin doses* | 262 ± 5 | 10.1 ± 0.3 | 95.3 ± 2.9 | 24,921 ± 768 | 3,697 ± 80 | −1,816 ± 65 |
2. Effect of edema toxin inhibition with PA mAb† | 277 ± 4 | 9.7 ± 0.3 | 86.1 ± 1.7 | 23,906 ± 587 | 2,888 ± 81 | −1,658 ± 43 |
3. Effect of edema toxin inhibition with adefovir‡ | 289 ± 9 | 10.0 ± 0.3 | 96.0 ± 4.9 | 26,812 ± 1696 | 3,130 ± 116 | 1,667 ± 67 |
Values are means ± SE.
Controls included animals receiving diluents of edema toxin or PA alone.
Controls included animals receiving toxin diluents with PA-mAb, PA alone, or PA with PA mAb.
Controls included animals receiving toxin diluents with adefovir or PA with diluents of adefovir.