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Systolic blood pressure of normotensive rats (NORM; n = 19), ANG rats (n = 19), ANG rats with triple therapy (ANG + TT; n = 21), and ANG rats with tetrahydrobiopterin (ANG + BH4; n = 21) before and after 1 and 2 wk of ANG II infusion. *Significant difference vs. NORM at each period (P ≤ 0.05). †Significant difference vs. ANG at each period (P ≤ 0.05).
