Table 3.
% α-MHC | Time Required to Reach Peak Force, ms | % Decrease in Time to Peak Force Compared with 0% α-MHC | Fold Decrease in Time to Peak Force Compared with 0% α-MHC |
---|---|---|---|
0 | 120.0 | 1 | |
10 | 85.4 | 28.8 | 0.71 |
20 | 74.4 | 38.0 | 0.62 |
30 | 69.4 | 42.1 | 0.58 |
Data were obtained from model predictions of twitch time courses in myocardium with variable ratios of α-MHC and β-MHC. Fold decrease in time to peak force from 0% α-MHC was computed as the ratio of the time to peak force from 10%, 20%, and 30% α-MHC to 0% α-MHC.