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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Hypertension. 2010 Sep 13;56(5):950–955. doi: 10.1161/HYPERTENSIONAHA.110.157115

Table 2.

Maximal relaxation responses and EC50 values of vessels incubated with acetylcholine to Ach of mesenteric arteries from vehicle, Ang II, tempol, tempo with Ang II infusion rats

Response Maximum (%) Maximum (%) P Log EC50 (mol/L) Log EC50 (mol/L) P
Vehicle Ang II

Ach 83.9 ± 7.9 36.0 ± 7.0 <0.01 −6.17 ± 0.06 −5.47 ± 0.04 <0.005
EDRF 54.4 ± 4.6 18.0 ± 4.7 <0.01 −6.55 ± 0.06 −5.78 ± 0.05 <0.005
EDHF 29.4 ± 2.7 18.7 ± 2.7 <0.05 −5.18 ± 0.07 −5.46 ± 0.16 ns
EDCF 5.2 ± 4.6 23.0 ± 5.6 <0.05 −4.11 ± 0.35 −4.49 ± 0.03 <0.005

Tempol Tempol-Ang II

Ach 88.9 ± 7.9 69.9 ± 8.9 ns −6.21 ± 0.05 −6.16 ± 0.08 ns
EDRF 53.4 ± 5.7 41.4 ± 4.7 ns −6.76 ± 0.09 −6.67 ± 0.01 ns
EDHF 35.4 ± 3.7 27.4 ± 4.7 ns −5.38 ± 0.15 −5.15 ± 0.14 ns
EDCF 5.1 ± 6.2 10.4 ± 4.6 ns −4.16 ± 0.13 −4.44 ± 0.07 ns

Data were obtained from experiments described in Figure 1.