Table 3.

Effects of angiotensin II infusion alone or during tempol administration on mesenteric resistance arterioles

Variable	Sham	Ang II	Tempol	Tempol + Ang II
NO activity with Ach (F/Fo DAF)	1.6 ± 0.2	1.0 ± 0.1‡	1.7 ± 0.2	1.3 ± 0.1
ROS activity with Ach (F/Fo tempo 9AC)	0.15 ± 0.03	0.82 ± 0.05‡	0.22 ± 0.05	0.42 ± 0.11
L-arginine (nmol · mg protein −1)	71 ± 25	95 ± 23	33 ± 4	57 ± 8*
ADMA (pmol · mg protein −1)	260 ± 35	450 ± 50†	228 ± 36	312 ± 36
SDMA (pmol · mg protein −1)	80 ± 50	127 ± 76	56 ± 9	103 ± 28
DDAH-2 protein (relative to β-actin)	1.4 ± 0.2	0.7 ± 0.1‡	1.2 ± 0.3	1.1 ± 0.2

Mean ± SEM values (n=6 per group) for mesenteric resistance arterioles. Effects of angiotensin II:

^*P<0.05;

^†P<0.01;

^‡P<0.005.