Table 4A.
Maximal endothelium-dependent hyperpolarization responses in mesenteric resistance arterioles from sham-infused rats
Added to the bath | Relaxation (%) | P value vs vehicle |
---|---|---|
Vehicle | 29 ± 3 | |
Catalase (125 units · ml−1) | 26 ± 6 | ns |
14,15-EEZE (10−5M) | 32 ± 5 | ns |
Endothelium removal | 1 ± 5 | P<0.005 |
Mean ± SEM values (n=6 per group). All vessels were preconstricted with 10−5 mol · l−1 norepinephrine, pretreated with 10−4 mol · l−1 l-nitroarginine to inhibit nitric oxide synthase and relaxed with 10−4 mol · l−1 acetylcholine. ns = not significant