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Precision of the LC-ESI-MS/MS method for analysis of Acr-dGuoa.
| Acr-dGuo level in calf thymus DNA (adducts/109 nucleotides) |
Interday average | Interday %RSD | |||
|---|---|---|---|---|---|
| Day 1 (mean ± SD) | Day 2 (mean ± SD) | Day 3 (mean ± SD) | |||
| α-OH-Acr-dGuo | 22 ± 1 | 21 ± 4 | 20 ± 3 | 21 ± 1 | 5.7 |
| γ-OH-Acr-dGuo | 67 ± 3 | 66 ± 7 | 69 ± 4 | 67 ± 2 | 2.3 |
Calf thymus DNA samples (150–450 μg) were analyzed in triplicate on each day.
