Table 5.
Effect Modification of the Association between Hypertension, Pre-hypertension* and Ethnicity by Body mass Index, Pediatric Task Force Data
| Boys | Girls | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Normal Weight † | Overweight † | Normal Weight † | Overweight † | |||||||||||
| Ethnic Group | OR∥ (95% CI) |
p-value‡ | OR∥ (95% CI) |
p-value‡ | p, interaction§ | OR∥ (95% CI) |
p-value‡ | OR∥ (95% CI) |
p-value‡ | p, interaction§ | ||||
| Hypertension | ||||||||||||||
| Caucasian | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | ||||||||||
| African-American | 1.14 (1.03–1.27) |
0.01 | 0.90 (0.78–1.05) |
0.20 | 0.01 | 1.08 (0.97–1.20) |
0.14 | 0.97 (0.85–1.11) |
0.69 | 0.22 | ||||
| Hispanic | 1.18 (1.00–1.39) |
0.05 | 1.23 (1.02–1.48) |
0.03 | 0.74 | 0.84 (0.70–1.01) |
0.06 | 0.96 (0.79–1.16) |
0.67 | 0.31 | ||||
| Pre-hypertension | ||||||||||||||
| Caucasian | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) | ||||||||||
| African-American | 1.28 (1.17–1.39) |
<0.001 | 1.02 (0.83–1.25) |
0.83 | 0.05 | 1.32 (1.17–1.49) |
<0.001 | 0.99 (0.82–1.21) |
0.93 | 0.01 | ||||
| Hispanic | 1.06 (0.92–1.23) |
0.41 | 0.83 (0.64–1.08) |
0.17 | 0.11 | 0.82 (0.66–1.02) |
0.08 | 0.73 (0.55–0.99) |
0.04 | 0.57 | ||||
Hypertension = ≥ the 95th percentile for either systolic or diastolic BP based on quantile regression methods; pre-hypertension = either systolic or diastolic pre-hypertension and not hypertensive
Normal weight = < 85th percentile; overweight = ≥ 85th percentile
Based on PROC GENMOD of SAS
P-value for interaction of ethnicity x Normal weight/overweight
Odds ratio for hypertension (pre-hypertension) for overweight vs. normal weight children