Table 2.
Assessing of clinical impact in two patients groups (newly diagnosed/follow-up), according to different scales used
| Scale | Characteristics | Total (n = 790, 100.0%) | Newly diagnosed (n = 124, 15.7%) | Follow-up (n = 666, 84.3%) | P value |
|---|---|---|---|---|---|
| HAM-A | Intensity of the categorised anxiety | < 0.001 | |||
| Intense (> 24) | 45.2% | 56.9% | 43.0% | ||
| Moderate (16-24) | 33.8% | 38.2% | 32.9% | ||
| Mild (10-15) | 11.3% | 4.1% | 12.6% | ||
| Without anxiety (0-9) | 9.8% | 0.8% | 11.4% | ||
| Subscale for psychic anxiety | 12.3 (4.9) | 14.2 (3.6) | 12.0 (5.0) | < 0.001 | |
| Subscale for somatic anxiety | 10.8 (5.2) | 12.6 (4.5) | 10.4 (5.2) | < 0.001 | |
| Total scoring | 23.1 (9.4) | 26.8 (7.3) | 22.4 (9.6) | < 0.001 | |
| CGI | Psychiatrist | 3.8 (1.1) | 4.2 (0.8) | 3.7 (1.1) | < 0.001 |
| Patient | 4.2 (1.3) | 4.7 (1.0) | 4.1 (1.3) | < 0.001 | |
| SDI | Incapacity for work | 5.3 (2.7) | 5.7 (2.4) | 5.3 (2.8) | NS |
| Incapacity for social life | 5.6 (2.6) | 5.9 (2.2) | 5.5 (2.6) | NS | |
| Incapacity for family relationships | 5.1 (2.5) | 5.6 (2.2) | 5.1 (2.6) | NS | |
| General incapacity (work-social-family) | 16.0 (7.0) | 17.1 (6.0) | 15.9 (7.2) | NS | |
| Perceived stress | 5.3 (2.3) | 5.7 (2.1) | 5.2 (2.4) | 0.032 | |
| Perceived social support | 56.1 (26.1) | 59.0 (23.9) | 55.7 (26.4) | NS | |
| SF-36 | Physical health summary index | 43.3 (9.0) | 43.3 (8.9) | 43.3 (9.1) | NS |
| Z Punctuation physical health summary index | -0.7 (0.9) | -0.7 (0.9) | -0.7 (0.9) | NS | |
| Mental health summary index | 30.0 (11.4) | 25.4 (8.5) | 30.8 (11.7) | < 0.001 | |
| Z Punctuation mental health summary index | -2.0 (1.1) | -2.5 (0.8) | -1.9 (1.2) | < 0.001 | |
Values are expressed as mean (SD) or percentages.
CGI = clinical global impression of disease; HAM-A = Hamilton Anxiety scale (HAM-A); NS = not significant SDS = Sheeham Disability Scale (SDS); SF-36 = 36-item short-form health-related quality of life questionnaire.