Table 4.
Correlation between PAI-1 and tPA activities and antigens and tPA/PAI-1 complex parameters among normal group (n = 131)
| Parameters | Adjusted for | PAI-1 activity (IU/ml) | PAI-1 antigen (ng/ml) | tPA activity (U/ml) | tPA antigen (ng/ml) | tPA/PAI-1complex (ng/ml) |
|---|---|---|---|---|---|---|
| PAI-1 activity | Age, gender, race, BMI, HDL-c & HOMA (IR) | 1 | 0.085(0.973) | 0.051(0.276) | -0.100(0.598) | 0.035(0.552) |
| PAI-1 antigen | Age, gender, race, HDL-c & HOMA (IR) | 1 | 0.044(0.60) | 0.111(0.642) | 0.029(0.03) | |
| tPA activity | Age, gender, race & FBS | 1 | -0.444(7.7 × 10-13) | -0.090(0.001) | ||
| tPA antigen | Age, gender, race & IS | 1 | 0.202(3.5 × 10-7) |
Result presented as adjusted r2 (P-value) assessed by Linear regression. Bolt values are significant.