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. 2011 Mar 25;6(3):e17924. doi: 10.1371/journal.pone.0017924

Table 1. p15 and clusterin expression in human pituitary adenomas.

p15 n (%) Clusterin n (%)
Intensity (%) 0–5 6–50 51–100 0–5 6–50 51–100
Tumor Types n n
GH/PRL 27 16(59) 4(15) 7(26) 17 13(76) 3(18) 1(6)
Gonadotroph 43 8(18) 5(12) 30(70) 36 1(3) 2(6) 33(92)
ACTH 14 2(14) 1(7) 11(79) 10 1(10) 0(0) 9(90)
Carcinoma N/A 12 9(76) 2(16) 1(8)
Normal pituitary 5 1(20) 2(40) 2(40) 4 2(50) 2(50) 0(0)

Protein distribution differences between GH/PRL and gonadotroph tumors, p = 0.0006 for p15, and p = 0.0001 for clusterin (Wilcoxon Rank Sum Test). N/A- not available.