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Genetic Profiles of Human GBM Xenografts Used in This Study
| Xenograft | EGFR | PTEN | p53 | p16 | MGMT |
|---|---|---|---|---|---|
| GBM 6 | Amplified (vIII) | Null | wt | Null | Nonhypermethylated |
| GBM 8 | Amplified (wt) | Null | wt | Null | Hypermethylated |
| GBM 12 | Amplified (wt) | wt | Null | Null | Hypermethylated |
| GBM GS-2 | Nonamplified | Null | Mutant | Unknown | Unknown |
| GBM 39 | Amplified (vIII) | wt | wt | Null | Hypermethylated |
wt, wild type.
