Figure 1.
Fabrication of molecular imprinted protein nanosensor. a, Schematic of nanosensor fabrication and template protein detection (see Methods for details). The supporting polymer (SU8-2002) is spin-coated on a glass substrate containing nanotube arrays. Template proteins trapped in the polyphenol (PPn) coating are removed to reveal the surface imprints. Inset meter shows hypothetical sensor impedance responses at critical stages of the fabrication and detection. b, Scanning electron microscopy image of a polished nanotube array after PPn coating. Inset: Cross section of nanotube tip after polishing. c, Transmission electron microscopy images of PPn-coated nanotube tip without (top) and with (bottom) hFtn.
