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A schematic representation of the development of normal spermatogenesis (top) and testicular germ cell tumorigeneis (bottom). CIS: carcinoma in situ; EC: embryonal carcinoma; TE: teratoma; YS: yolk sac tumour; TGCT: testicular germ cell tumours; NS: non-seminoma; SE: seminoma; SS: spermatocytic seminoma; ITNS: intratubular non-seminoma; ITSE: intratubular seminoma.
