Preclinical MR-guided FUS of the prostate. Three images from an animal study show, A, axial phase image with thermal change (high-signal-intensity area centrally) from an individual sonication delivered by transrectal FUS transducer device (Insightec), then, B, axial T1-weighted and, C, sagittal T1-weighted images after the procedure and after injection of intravenous gadolinium show the focal ablation as an area of nonperfusion (yellow).