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. 2011 Feb;20(2):231–237. doi: 10.1089/jwh.2010.2114

Table 2.

Predictors of Breast Cancer and All-Cause Mortality in Women with Breast Cancer

 
Breast cancer mortality
All-cause mortality
Characteristic HR CI p HR CI p
Ethnicity            
 Japanese 1.00     1.00    
 Caucasian 0.39 0.13-1.16 0.09 1.03 0.60-1.75 0.92
 Chinese 2.28 0.86-6.03 0.10 1.49 0.81-2.76 0.20
 Filipino 1.68 0.50-5.67 0.40 1.76 0.79-3.95 0.17
 Hawaiian 0.60 0.20-1.86 0.38 1.29 0.66-2.53 0.45
 Other 1.57 0.45-5.44 0.48 1.52 0.72-3.20 0.27
Age at diagnosis (years)            
 25–<50 1.00     1.00    
 50–<60 2.48 0.83-7.42 0.10 1.07 0.47-2.48 0.87
 60–<70 1.60 0.41-6.32 0.50 1.19 0.46-3.07 0.72
 70–95 1.08 0.26-4.51 0.92 3.19 1.28-7.93 0.01
Menopausal status            
 Premenopausal 1.00     1.00    
 Postmenopausal 0.80 0.28-2.33 0.69 1.19 0.52-2.72 0.69
Body mass index (kg/m2)            
 <18.5 2.16 0.64-7.35 0.22 0.99 0.41-2.38 0.99
 18.5–<25 1.00     1.00    
 25–<30 0.92 0.38-2.23 0.85 0.98 0.60-1.60 0.94
 ≥30 2.99 1.22-7.33 0.02 2.06 1.23-3.44 0.006
Tumor stage            
 0–I 1.00     1.00    
 IIA 3.08 1.14-8.33 0.03 1.84 1.05-3.22 0.03
 IIB–IV 11.2 4.97-25.3 <0.0001 3.72 2.27-6.09 <0.0001
Hormonal status            
 ER+/PR+ 1.00     1.00    
 ER+/PR− and ER−/PR+ 1.08 0.35-3.32 0.90 1.58 0.80-3.12 0.19
 ER−/PR−  0.88 0.39-2.01 0.76 1.07 0.62-1.86 0.80
PDQa            
 No 1.00     1.00    
 Yes 0.26 0.10-0.65 0.004 0.50 0.32-0.79 0.003
 Yes+ 0.75 0.32-1.74 0.51 0.72 0.42-1.21 0.21
High toxicity            
 No 1.00     1.00    
 Yes 2.13 0.94-4.84 0.07 1.27 0.69-2.33 0.44
Comorbidity            
 No 1.00     1.00    
 Yes 1.10 0.50-2.41 0.82 2.19 1.46-3.28 0.0002
Health insurance            
 Fee for service 1.00     1.00    
 HMO 1.66 0.85-3.25 0.14 1.23 0.81-1.87 0.32

Multivariate Cox's model adjusted for all other variables (hazard ratios and 95% confidence intervals).

a

Adherence to treatment guidelines according to Physicians Data Query; Yes+ indicates additional treatments.