Table 2.
|
Breast cancer mortality |
All-cause mortality |
||||
---|---|---|---|---|---|---|
Characteristic | HR | CI | p | HR | CI | p |
Ethnicity | ||||||
Japanese | 1.00 | 1.00 | ||||
Caucasian | 0.39 | 0.13-1.16 | 0.09 | 1.03 | 0.60-1.75 | 0.92 |
Chinese | 2.28 | 0.86-6.03 | 0.10 | 1.49 | 0.81-2.76 | 0.20 |
Filipino | 1.68 | 0.50-5.67 | 0.40 | 1.76 | 0.79-3.95 | 0.17 |
Hawaiian | 0.60 | 0.20-1.86 | 0.38 | 1.29 | 0.66-2.53 | 0.45 |
Other | 1.57 | 0.45-5.44 | 0.48 | 1.52 | 0.72-3.20 | 0.27 |
Age at diagnosis (years) | ||||||
25–<50 | 1.00 | 1.00 | ||||
50–<60 | 2.48 | 0.83-7.42 | 0.10 | 1.07 | 0.47-2.48 | 0.87 |
60–<70 | 1.60 | 0.41-6.32 | 0.50 | 1.19 | 0.46-3.07 | 0.72 |
70–95 | 1.08 | 0.26-4.51 | 0.92 | 3.19 | 1.28-7.93 | 0.01 |
Menopausal status | ||||||
Premenopausal | 1.00 | 1.00 | ||||
Postmenopausal | 0.80 | 0.28-2.33 | 0.69 | 1.19 | 0.52-2.72 | 0.69 |
Body mass index (kg/m2) | ||||||
<18.5 | 2.16 | 0.64-7.35 | 0.22 | 0.99 | 0.41-2.38 | 0.99 |
18.5–<25 | 1.00 | 1.00 | ||||
25–<30 | 0.92 | 0.38-2.23 | 0.85 | 0.98 | 0.60-1.60 | 0.94 |
≥30 | 2.99 | 1.22-7.33 | 0.02 | 2.06 | 1.23-3.44 | 0.006 |
Tumor stage | ||||||
0–I | 1.00 | 1.00 | ||||
IIA | 3.08 | 1.14-8.33 | 0.03 | 1.84 | 1.05-3.22 | 0.03 |
IIB–IV | 11.2 | 4.97-25.3 | <0.0001 | 3.72 | 2.27-6.09 | <0.0001 |
Hormonal status | ||||||
ER+/PR+ | 1.00 | 1.00 | ||||
ER+/PR− and ER−/PR+ | 1.08 | 0.35-3.32 | 0.90 | 1.58 | 0.80-3.12 | 0.19 |
ER−/PR− | 0.88 | 0.39-2.01 | 0.76 | 1.07 | 0.62-1.86 | 0.80 |
PDQa | ||||||
No | 1.00 | 1.00 | ||||
Yes | 0.26 | 0.10-0.65 | 0.004 | 0.50 | 0.32-0.79 | 0.003 |
Yes+ | 0.75 | 0.32-1.74 | 0.51 | 0.72 | 0.42-1.21 | 0.21 |
High toxicity | ||||||
No | 1.00 | 1.00 | ||||
Yes | 2.13 | 0.94-4.84 | 0.07 | 1.27 | 0.69-2.33 | 0.44 |
Comorbidity | ||||||
No | 1.00 | 1.00 | ||||
Yes | 1.10 | 0.50-2.41 | 0.82 | 2.19 | 1.46-3.28 | 0.0002 |
Health insurance | ||||||
Fee for service | 1.00 | 1.00 | ||||
HMO | 1.66 | 0.85-3.25 | 0.14 | 1.23 | 0.81-1.87 | 0.32 |
Multivariate Cox's model adjusted for all other variables (hazard ratios and 95% confidence intervals).
Adherence to treatment guidelines according to Physicians Data Query; Yes+ indicates additional treatments.