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. 2010 Jun 20;67(4):829–835. doi: 10.1007/s00280-010-1384-z

Table 6.

Multivariate Cox proportional hazards analysis for effectiveness of second-line chemotherapy on OS

Variable Adjusted HR 95% CI P value
Age (years) 0.081
 <60 1
 ≥60 0.497 0.228–1.085
Histology 0.40
 Endometrioid 1
 Non-endometrioid 1.497 0.590–3.800
Initial stage 0.30
 I/II 1
 III/IV 1.613 0.658–3.953
TFI 0.042
 ≥6 months 1
 <6 months 2.341 1.034–5.301

The adjusted HR of TFI < 6 months was 2.341 (95% CI, 1.034–5.301), compared to TFI ≥ 6 months, showing statistical significance (P = 0.042)

HR hazard ratio, TFI treatment-free interval