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. 2001 Mar 13;98(6):3304–3309. doi: 10.1073/pnas.051634098

Figure 4.

Figure 4

Neutralization of four different human IL-18 analogues by IL-18BP. (A) Each of the four IL-18 analogues was mixed with IL-18BP at the concentrations indicated under the horizontal axis for 1 h at room temperature and then added to NKOs that were stimulated with IL-12 at 0.5 ng/ml. (B) Each of the four IL-18 analogues was mixed with IL-18BP at the concentrations indicated under the horizontal axis for 1 h at room temperature and then added to PBMCs that were stimulated with IL-12 at 1.0 ng/ml. After 24 h, IFN-γ was measured at the concentration shown to the left of the vertical axes. The data represent mean ± SEM. n = 3.