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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Circ Cardiovasc Genet. 2010 Feb 2;3(2):187–198. doi: 10.1161/CIRCGENETICS.109.904813

Figure 2D. TH promoter haplotype activities. Statistical analyses were based on results from 8 naturally occurring haplotypes (haplotypes 1, 2, 3, 7, 8, 9, 11, and 13; on-line supplemental Table 1).

Figure 2D

TH promoter common variant C-824T: Functional variation under basal and stimulated circumstances. Experiments were conducted on two haplotype backgrounds. Bars show mean ± SEM luciferase activity for each state. C-824 (CGAA) is from haplotype-1, -824T (TGAA) from haplotype-13, C-824 (CGGG) from haplotype-8, and -824T (TGGG) from haplotype-2 (on-line supplemental Table 2). Results are shown as fold of basal (no drug treatment).