Table 1.

Characteristics of high-risk tumors. Adapted from NCCN Practice Guidelines in Oncology: Basal Cell and Squamous Cell Skin Cancers [36].

Size/Location:
(a) 10 mm (cheeks, forehead, scalp, neck)
(b) 6 mm3 (central face, eyelids, eyebrows, nose, lips, chin, ear, temple)
Poorly defined borders
Recurrent disease
Immunosuppression
Rapid Growth
Site of prior radiation, scar
Neurological symptoms
Pathologic Criteria:
(a)Moderately or poorly differentiated
(b) Adenoid (acantholytic), adenosquamous, or desmoplastic
(c) Depth:
Clark level IV, V
≥4 mm
(d) Perineural or vascular invasion