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. Author manuscript; available in PMC: 2011 Mar 28.
Published in final edited form as: J Nucl Med. 2009 Oct 16;50(11):1887–1894. doi: 10.2967/jnumed.109.065284

FIGURE 7.

FIGURE 7

Kinetics of brain uptake and washout in rhesus monkey after intravenous injection of 18F-AV-45 (173.9 MBq [4.7 mCi]) are presented. It is evident that uptake in cortex peaked at 7 min, and activity was washed out quickly thereafter. White matter area also displayed good initial uptake, and washout rate was also rapid. It is estimated that brain uptake at peak was about 4.4% of injected dose, which suggested that 18F-AV-45 penetrated normal blood–brain barrier efficiently.