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. 2011 Feb 20;2010:540940. doi: 10.1155/2010/540940

Figure 2.

Figure 2

High-frequency stimulation of the MGm/PIN promotes ERK-driven IEG expression in both the LA and MGm/PIN. (a) Placement of stimulation electrode and schematic of the experimental protocol. Rats were given HFS or LFS and sacrificed 2 hours after stimulation. (b) Images of Western blots for Arc/Arg3.1, c-Fos, EGR-1, and GAPDH from both LA (top) and MGm/PIN samples (bottom). (c) Mean (±SEM) percent IEG immunoreactivity from LA punches taken from rats given HFS (n = 9) or LFS (n = 9). (d) Mean (±SEM) percent IEG immunoreactivity from MGm/PIN punches taken from rats given HFS (n = 9) or LFS (n = 9). In each figure, IEG levels have been normalized to GAPDH for each sample, and IEG expression on the ipsilateral side has been expressed as a percentage of that on the contralateral side for each rat. *P < .05 relative to the ipsilateral side N.S. = not significant.