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. 2011 Feb 20;2010:540940. doi: 10.1155/2010/540940

Figure 8.

Figure 8

Pharmacological blockade of extracellular NO in the LA impairs ERK-driven IEG expression in the MGm/PIN, but not the LA, following HFS. (a) Images of Western blots for Arc/Arg3.1, c-Fos, EGR-1, and GAPDH from both LA (top) and MGm/PIN (bottom) samples. (b) Mean (±SEM) percent Arc/Arg3.1, c-Fos, and EGR-1 immunoreactivity from LA punches taken from rats given intra-LA infusion of 50% DMSO (vehicle; n = 8) or 1 μg/side c-PTIO (n = 8). (C) Mean (±SEM) percent Arc/Arg3.1, c-Fos and EGR-1 immunoreactivity from MGm/PIN punches taken from rats given intra-LA infusion of 50% DMSO (vehicle; n = 8) or 1 μg/side c-PTIO (n = 8). In each figure, IEG levels have been normalized to GAPDH for each sample, and IEG expression on the ipsilateral side has been expressed as a percentage of that on the contralateral side for each rat. *P < .05 relative to the ipsilateral side N.S. = not significant.