Table 1.
Demographic and clinical characteristics and their association with AD+P.
| Variable | Psychosis Status | Total N (%) or mean (SD) | χ2† or F‡ | df | P value | ||
|---|---|---|---|---|---|---|---|
| Never N (%) or mean (SD) | Single N (%) or mean (SD) | Multiple/Recurrent N (%) or mean (SD) | |||||
| Age | 78.2 (6.8) | 79.0 (7.1) | 78.3 (7.1) | 78.4 (6.9) | 2.197‡ | .111 | |
| Age of onset | 73.3 (6.9) | 73.4 (7.1) | 72.3 (6.9) | 73.2 (6.9) | 2.862‡ | .057 | |
| Sex | 15.673† | 2 | <.001 | ||||
| Male | 704 (46.5) | 188 (38.1) | 116 (37.5) | 1008 (43.5) | |||
| Female | 811 (53.5) | 305 (61.9) | 193 (62.5) | 1309 (56.5) | |||
| Race | 82.409† | 4 | <.001 | ||||
| Caucasian | 1347 (89.0) | 394 (80.0) | 216 (70.0) | 1957 (84.5) | |||
| African-American | 132 (8.7) | 76 (15.4) | 69 (22.3) | 277 (12.0) | |||
| Other | 35 (2.3) | 23 (4.6) | 24 (7.7) | 82 (3.5) | |||
| Hispanic | 21.161† | 2 | <.001 | ||||
| No | 1429 (94.3) | 448 (90.9) | 270 (87.4) | 2147 (92.7) | |||
| Yes | 86 (5.7) | 45 (9.1) | 39 (12.6) | 170 (7.3) | |||
| Primary language | 13.100† | 2 | .001 | ||||
| English | 1425 (94.1) | 455 (92.3) | 273 (88.3) | 2153 (92.9) | |||
| Other | 90 (5.9) | 38 (7.7) | 36 (11.7) | 164 (7.1) | |||
| Education | 14.2 (3.6) | 13.4 (3.6) | 13.0 (4.2) | 13.8 (3.7) | 19.138‡ | <.001 | |
| MMSE | 18.7 (6.7) | 16.8 (7.0) | 14.2 (7.1) | 17.7 (7.0) | 59.922‡ | <.001 | |
| CDR (global) | 177.772† | 8 | <.001 | ||||
| 0.0 | 12 (0.8) | 0 (0.0) | 0 (0.0) | 12 (0.5) | |||
| 0.5 | 364 (24.0) | 52 (10.5) | 12 (3.9) | 428 (18.5) | |||
| 1.0 | 583 (38.5) | 192 (39.0) | 83 (26.9) | 858 (37.0) | |||
| 2.0 | 408 (26.9) | 182 (36.9) | 132 (42.7) | 722 (31.2) | |||
| 3.0 | 148 (9.8) | 67 (13.6) | 82 (26.5) | 297 (12.8) | |||
| Hachinski | 1.1 (1.4) | 1.1 (1.3) | 1.3 (1.5) | 1.1 (1.4) | 2.417‡ | .089 | |
| GDS | 2.2 (2.4) | 2.5 (2.8) | 2.7 (3.0) | 2.3 (2.6) | 6.849‡ | .001 | |
| APOE ϵ4 allele carrier status | 4.008† | 2 | .135 | ||||
| −ϵ4 | 632 (41.7) | 190 (38.5) | 112 (36.2) | 934 (40.3) | |||
| +ϵ4 | 883 (58.3) | 303 (61.5) | 197 (63.8) | 1383 (59.7) | |||
| APOE ϵ4 allele number | 5.097† | 4 | .277 | ||||
| 0 | 632 (41.7) | 190 (38.5) | 112 (36.3) | 934 (40.3) | |||
| 1 | 712 (47.0) | 236 (47.9) | 158 (51.1) | 1106 (47.7) | |||
| 2 | 171 (11.3) | 67 (13.6) | 39 (12.6) | 277 (12.0) | |||
Abbreviations: AD+P, Alzheimer's disease plus psychosis; MMSE, Mini-mental state exam; CDR, Clinical dementia rating scale; GDS, Geriatric depression scale; APOE, Apolipoprotein E.
†Pearson's Chi-square test: χ2 values are presented.
‡One-way analysis of variance: F values are presented.