(A–B) are the distributions of the log-ratios (heavy/medium, log10 based) obtained by MaxQuant for the newly synthesized peptides after 4 hr (A) and 48 hr (B) transfection, respectively. (C–D) are the distributions of the log-ratios (heavy/medium, log10 based) obtained by UNiquant for the newly synthesized peptides after 4 hr (C) and 48 hr (D) transfection, respectively. The newly synthesized peptides after microRNA transfection and mock GFP transfection are labeled with SILAC-M (medium), and SILAC-H (heavy), respectively.