Table 2.

Alterations in glucose metabolism after sleep loss: 2 laboratory studies

	p	% change from well-rested condition
5 nights of 4-hour bedtimes (n = 11)
Glucose tolerance (% · min-1)	≤0.003	–43 ± 12
Acute insulin response to glucose (μU · ml-1 · min)	≤0.03	–27 ±10
Glucose effectiveness	≤0.05	–25 ± 19
Insulin sensitivity, 104 min-1 (μU/ml)-1	≤0.04	–24 ± 9
Disposition index	0.004	–50 ± 6
3 nights of slow-wave sleep suppression (n = 9)
Glucose tolerance, % · min-1	≤0.03	–23 ± 9
Acute insulin response to glucose, μU · ml-1 · min	≤0.73	+11 ± 11
Glucose effectiveness	≤0.19	–15 ± 10
Insulin sensitivity, 104 min-1 (μU/ml)-1	≤0.009	–25 ± 8
Disposition index	≤0.02	–20 ± 7