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. Author manuscript; available in PMC: 2011 Mar 28.
Published in final edited form as: Angew Chem Int Ed Engl. 2008;47(51):9951–9954. doi: 10.1002/anie.200803834

Figure 3.

Figure 3

(a) An AFM topography of the PEG pattern used for fabricating a flat stamp for μCP of proteins. (b) A fluorescent image of the printed TRITC conjugated anti-mouse IgG. (c) A fluorescent image of the printed TRITC pattern on glass.

The intrinsic drawbacks in conventional microcontact printing, i.e. roof collapse and lateral ink diffusion, were addressed by using topographically flat, chemically patterned PDMS stamps made by Dip-Pen Nanolithography (DPN). The chemically patterned flat stamps were used for contact printing of various inks including thiols, proteins and hydrophilic dyes. The as-made features can reach sub-100 nm resolution and very low filling factor (<1/100).##DPN benefits μCP

dip-pen nanolithography

microcontact printing

silanes

nanofabrication

surface chemistry