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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2011 Apr;56(4):312–319. doi: 10.1097/QAI.0b013e31820c011a

TABLE 2.

Univariate and Multivariate Associations with Early (One Year) Mortality by Cox Proportional Hazards Model

Univariate Modelsa
Adjusted Modelsb
HR (95% CI) P HR (95% CI) P
Cumulative doses of chemotherapy w/in 105 days, n = 160 0.94 (0.77, 1.13) 0.49 0.96 (0.79, 1.18) 0.72
Age (year) 0.99 (0.98, 1.00) 0.18
Gender, n = 160:
 Female Reference Reference
 Male 0.67 (0.41, 1.12) 0.12 0.58 (0.34, 1.01) 0.053
BMI (among those 18 years or older), n = 107
 <18.5 Reference
 >18.5 0.70 (0.36, 1.36) 0.29
Tumor Stage, n = 160:
 I Reference
 II 1.32 (0.18, 9.45) 0.78
 III 1.25 (0.28, 5.55) 0.77
 IV 1.55 (0.36, 6.64) 0.55
 Unknown 2.17 (0.50, 9.41) 0.30
Tumor Stage, n = 160:
 I & II Reference
 III & IV 1.25 (0.44, 3.52) 0.67
 Unknown 1.91 (0.65, 5.62) 0.24
Preexisting HIV WHO staging illness* (among HIV+ participants), n = 40:
 I & II Reference
 III & IV 0.29 (0.10, 0.88) 0.029
 Unknown 0.77 (0.23, 2.55) 0.67
HIV Category, n = 154
 Negative Reference Reference
 Positive, no ARV treatment 5.37 (2.30, 12.53) <0.001 8.99 (3.62, 22.34) <0.001
 Positive, any ARV 1.04 (0.56, 1.96) 0.89 1.14 (0.57, 2.30) 0.71
 Unknown 2.25 (0.98, 5.13) 0.055 2.04 (0.82, 5.04) 0.12
Hemoglobin (g/dl) n = 152 0.89 (0.82, 0.97) 0.005 0.88 (0.80, 0.97) 0.008
LDH, n = 100
 <300 Reference
 ≥300 0.95 (0.47, 1.91) 0.88
CD4 Count (cells/uL) (among HIV+ participants), n = 37
 ≤200 Reference
 >200 0.62 (0.21, 1.87) 0.40
B-Symptoms, n = 160 1.99 (0.98, 4.05) 0.056 2.08 (1.00, 4.31) 0.050

BMI, body mass index categorized according to WHO44,45; WHO, World Health Organization; HIV, human immunodeficiency virus; LDH, lactate dehydrogenase; ARV, Antiretroviral.

*

had or had had another WHO stage-defining illness NHL diagnosis

a

= Number of observations in each the bivariate model are indicated by the different numbers, n

b

(146) = No. of observations used in the multivariate model.