TABLE 2.
Univariate and Multivariate Associations with Early (One Year) Mortality by Cox Proportional Hazards Model
Univariate Modelsa |
Adjusted Modelsb |
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---|---|---|---|---|---|---|
HR | (95% CI) | P | HR | (95% CI) | P | |
Cumulative doses of chemotherapy w/in 105 days, n = 160 | 0.94 | (0.77, 1.13) | 0.49 | 0.96 | (0.79, 1.18) | 0.72 |
Age (year) | 0.99 | (0.98, 1.00) | 0.18 | |||
Gender, n = 160: | ||||||
Female | Reference | Reference | ||||
Male | 0.67 | (0.41, 1.12) | 0.12 | 0.58 | (0.34, 1.01) | 0.053 |
BMI (among those 18 years or older), n = 107 | ||||||
<18.5 | Reference | |||||
>18.5 | 0.70 | (0.36, 1.36) | 0.29 | |||
Tumor Stage, n = 160: | ||||||
I | Reference | |||||
II | 1.32 | (0.18, 9.45) | 0.78 | |||
III | 1.25 | (0.28, 5.55) | 0.77 | |||
IV | 1.55 | (0.36, 6.64) | 0.55 | |||
Unknown | 2.17 | (0.50, 9.41) | 0.30 | |||
Tumor Stage, n = 160: | ||||||
I & II | Reference | |||||
III & IV | 1.25 | (0.44, 3.52) | 0.67 | |||
Unknown | 1.91 | (0.65, 5.62) | 0.24 | |||
Preexisting HIV WHO staging illness* (among HIV+ participants), n = 40: | ||||||
I & II | Reference | |||||
III & IV | 0.29 | (0.10, 0.88) | 0.029 | |||
Unknown | 0.77 | (0.23, 2.55) | 0.67 | |||
HIV Category, n = 154 | ||||||
Negative | Reference | Reference | ||||
Positive, no ARV treatment | 5.37 | (2.30, 12.53) | <0.001 | 8.99 | (3.62, 22.34) | <0.001 |
Positive, any ARV | 1.04 | (0.56, 1.96) | 0.89 | 1.14 | (0.57, 2.30) | 0.71 |
Unknown | 2.25 | (0.98, 5.13) | 0.055 | 2.04 | (0.82, 5.04) | 0.12 |
Hemoglobin (g/dl) n = 152 | 0.89 | (0.82, 0.97) | 0.005 | 0.88 | (0.80, 0.97) | 0.008 |
LDH, n = 100 | ||||||
<300 | Reference | |||||
≥300 | 0.95 | (0.47, 1.91) | 0.88 | |||
CD4 Count (cells/uL) (among HIV+ participants), n = 37 | ||||||
≤200 | Reference | |||||
>200 | 0.62 | (0.21, 1.87) | 0.40 | |||
B-Symptoms, n = 160 | 1.99 | (0.98, 4.05) | 0.056 | 2.08 | (1.00, 4.31) | 0.050 |
BMI, body mass index categorized according to WHO44,45; WHO, World Health Organization; HIV, human immunodeficiency virus; LDH, lactate dehydrogenase; ARV, Antiretroviral.
had or had had another WHO stage-defining illness NHL diagnosis
= Number of observations in each the bivariate model are indicated by the different numbers, n
(146) = No. of observations used in the multivariate model.