Table 1.

CXCR3 and its ligands in human disease and murine disease models

Human Disease	[ref]	Mouse Models	CXCR3	CXCL9	CXCL10	[ref]
Autoimmmune
Psoriasis	[78–80]
Sarcoid	[81–83]
Rheumatoid Arthritis	[7, 10, 84–86]	Adjuvant-induced arthritis	√		√	[34, 35]
Asthma	[87–89]	Allergic Pulmonary Inflammation	√	√	√	[90, 91]
Atherosclerosis	[92]	ApoE−/−, LDLR−/−	√		√	[63, 93]
Multiple Sclerosis	[94–96]	EAE	√		√	[61, 97–101]
IBD	[102]	IL-10−/−, RBhi transfer	√		√	[103]
Idiopathic Pulmonary Fibrosis	[104]	Bleomycin-induced injury	√		√	[105–107]
Type I Diabetes Mellitus	[108, 109]	Insulitis	√	√	√	[36, 110]
SLE	[111–113]	MRL/lpr	√	√	√	[37]
Cigarette smoke injury/COPD	[114, 115]	Cigarette smoke injury	√			[116, 117]
		Myocarditis	√		√	[25, 118]
Transplantation
Heart Transplant	[119, 120]	Orthotopic Heart Transplant	√	√	√	[44, 121–125]
Lung Transplant	[126]	Orthotopic Tracheal Transplant	√	√	√	[43, 127]
GVH	[128]	GVH	√		√	[129]
		Small Bowel			√	[130]
Infections
Leprosy	[131]
Tuberculosis	[132, 133]
		Influenza	√			[134, 135]
		Toxoplasma gondii	√		√	[18, 136]
Malaria (P. falciparium)	[137]	Malaria (P. berghei)	√	√	√	[26, 27]
Dengue	[138]	Dengue	√		√	[139]
Hepatitis B and C	[140–142]	Mouse Hepatitis Virus			√	[68, 143]
Herpes Simplex	[144]	Herpes Simplex	√	√	√	[29–31, 145]
HIV-1	[146–148]
Leishmania	[149]	Leishmania	√		√	[150, 151]
		Chlamydia Trachomatis	√			[152, 153]
Lyme	[154, 155]	Lyme	√			[156]
		Klebsiealla			√	[157]
West Nile Virus						[28]
Cancer
Renal	[158]	Renal	√	√		[86]
Colon	[159]	Colon			√	[160]
Melanoma	[161]	Melanoma		√	√	[161]
Lymphoma	[162–164]	Lymphoma			√	[165]
Breast	[166]	Breast	√		√	[166, 167]