Table 1.
Sham-Operated Rats | Uremic Rats |
||
---|---|---|---|
Nx-Vehicle | Nx-Celecoxib | ||
Diet | Phosphate 0.8% | Phosphate 1.2% | Phosphate 1.2% |
Number of rats | 20 | 17 | 18 |
Body weight (gram) | 645 ± 30.20 | 486 ± 19.60a | 540 ± 20.70a |
Serum creatinine (mg/dl) | 0.50 ± 0.04 | 1.27 ± 0.16a | 1.08 ± 0.14a |
BUN (mg/dl) | 27.13 ± 0.81 | 77.28 ± 10.08a | 66.33 ± 10.50a |
Serum calcium (mg/dl) | 9.50 ± 0.32 | 10.14 ± 0.24 | 9.94 ± 0.28 |
Serum phosphorus (mg/dl) | 7.37 ± 0.50 | 8.73 ± 0.81a | 7.80 ± 0.77a |
Intact PTH (pg/ml) | 22.65 ± 2.63 | 124.39 ± 8.38b | 88.20 ± 4.21d,b |
Data are mean ± SEM.
aP < 0.05 versus sham group;
dP < 0.05 versus Nx + vehicle group;
bP < 0.01 versus sham group.