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Immunolocalization of BMP1–1 and BMP1–3 in the liver and kidney during human development. In the liver at 7 weeks of gestation (frame; A) BMP1–1 was not present (B), whereas hepatocytes stained positively for BMP1–3 (C). At 7.5 weeks of gestation (E) BMP1–1 and (F) BMP1–3 were expressed in more mature tubules inside of the kidney (t; asterisk), but no labeling was found in the glomerulus (g) (frame; D). A and D magnification: ×1.5; B, C, E, and F magnification: ×40.
