Table 2. Univariate survival analysis (Kaplan–Meier estimates) according to clinico-pathological factors and BMI in 1129 endometrial carcinoma patients.
| Variable | No. of patients (no. of deaths)a | 5-year survival | P (log-rank) |
|---|---|---|---|
| Age, quartiles b | <0.0001 | ||
| 1 (age 27–58) | 282 (17) | 94.5 | |
| 2 (age 58–66) | 282 (44) | 84.4 | |
| 3 (age 66–74) | 283 (73) | 73.8 | |
| 4 (age 74–94) | 282 (89) | 63.8 | |
| Sum | 1129 | ||
| Menopausal status | <0.0001 | ||
| Pre/peri | 145 (13) | 93.9 | |
| Post | 983 (87) | 77.1 | |
| Sumc | 1128 | ||
| FIGO stage | <0.0001 | ||
| I | 812 (79) | 90.8 | |
| II | 119 (27) | 74.2 | |
| III | 132 (68) | 39.4 | |
| IV | 65 (48) | 16.3 | |
| Sumd | 1128 | ||
| Histological subtype | <0.0001 | ||
| Endometrioid | 966 (146) | 84.4 | |
| Non-endometrioid | 163 (77) | 46.8 | |
| Sum | 1129 | ||
| Grade | <0.0001 | ||
| 1 | 345 (26) | 92.0 | |
| 2 | 454 (81) | 82.6 | |
| 3 | 283 (105) | 56.9 | |
| Sume | 1082 | ||
| BMI WHO | 0.066f | ||
| Underweight (<18.5) | 23 (7) | 63.3 | |
| Normal (18.5–24.9) | 358 (77) | 77.0 | |
| Overweight (25–29.9) | 309 (51) | 81.9 | |
| Obese (⩾30) | 259 (47) | 81.1 | |
| Sumg | 949 | ||
| BMI quartiles | 0.096f | ||
| 1 (14.7–23.1) | 237 (54) | 75.3 | |
| 2 (23.1–26.3) | 240 (46) | 79.1 | |
| 3 (26.3–30.5) | 236 (39) | 81.3 | |
| 4 (30.5–73.0) | 236 (43) | 81.4 | |
| Sum | 949 | ||
| BMI 2 groups h | 0.035f | ||
| <25 | 381 (84) | 76.3 | |
| ⩾25 | 568 (98) | 81.6 | |
| Sum | 949 | ||
Abbreviations: BMI=body mass index; FIGO=International Federation of Gynaecology and Obstetrics; WHO=World Health Organization.
a
Number of patients varies due to missing data.
b
Truncated to closest integer.
c
Data for menopausal status missing for one patient.
d
Data for FIGO stage missing for one patient.
e
Data for grade missing for 67 patients.
f
P-value with linear trend test.
g
Data for BMI missing for 180 patients.
h
Endometrioid carcinomas only: 5-year survival: BMI<25=81.2%, BMI⩾25=85.6% (P=0.134).