Table 3. Survival analysis of 905 endometrial carcinoma patients based on the Cox proportional hazards model.
| Variable | No. of patients (%) | Unadjusted HRa | 95% CI | P-value | Adjusted HR | 95% CI | P-value |
|---|---|---|---|---|---|---|---|
| FIGO stage | <0.0001 | <0.0001 | |||||
| I | 646 (71) | 1.00 | 1.00 | ||||
| II | 96 (11) | 3.25 | 1.98–5.31 | 2.83 | 1.72–4.65 | ||
| III | 111 (12) | 9.75 | 6.73–14.12 | 8.13 | 5.52–11.97 | ||
| IV | 52 (6) | 32.60 | 21.10–50.35 | 24.41 | 14.80–40.26 | ||
| Histological subtype | <0.0001 | 0.08 | |||||
| Endometrioid | 777 (86) | 1.00 | 1.00 | ||||
| Non-endometrioid | 128 (14) | 4.76 | 3.44–6.57 | 1.49 | 0.95–2.32 | ||
| Grade | <0.0001 | 0.11 | |||||
| 1 or 2 | 668 (74) | 1.00 | 1.00 | ||||
| 3 | 237 (26) | 3.84 | 2.83–5.19 | 1.41 | 0.93–2.13 | ||
| Age b | 904 (100) | 1.06 | 1.04–1.07 | <0.0001 | 1.05 | 1.03–1.06 | <0.0001 |
| BMI c | 0.04 | 0.65 | |||||
| <25 | 364 (40) | 1.38 | 1.02–1.86 | 0.93 | 0.68–1.27 | ||
| ⩾25 | 541 (60) | 1.00 | 1.00 | ||||
Abbreviations: BMI=body mass index; CI=confidence interval; FIGO=International Federation of Gynaecology and Obstetrics; HR=hazard ratio.
a
Analyses based on patients with complete information for all variables (n=905).
b
Age at primary operation, continuous variable with HR given per year.
c
When including patients with endometrioid histology only: adjusted HR for BMI was 1.07, 95% CI 0.73–1.55, P=0.7.