Table 3.

Phenotypic Clues Linking Imaging to Non-HCM Genetic Cardiomyopathies^*

Imaging Phenotype	Additional Clinical Clues†	Genetic Considerations
Dilated cardiomyopathy with diastolic dysfunction, atrial myopathy	Conduction system disease	Lamin A/C
Dilated cardiomyopathy with circumferential or confluent midwall enhancement by LGE‡	Acute myocarditis-like presentation	Left-dominant arrhythmogenic cardiomyopathy
Right ventricular dilatation, segmental contraction abnormalities, aneurysms; fibrofatty changes in myocardium	Left bundle branch-morphology ventricular arrhythmia	Arrhythmogenic right ventricular cardiomyopathy

^*This summary relates to DCM and ARVC, and does not include findings related to hypertrophic cardiomyopathy or genetic cardiomyopathies associated with muscular dystrophies or inborn errors of metabolism.

^†A valuable clinical clue pointing to genetic cardiomyopathy may be obtained from a meticulous family history.

^‡LGE = late gadolinium enhancement imaging. Note that left-dominant arrhythmogenic cardiomoypathy may present with preserved LV size and systolic function as well.