Table 4.

Echo-Doppler and Neurohormones

	Exercise		Control		P-Value
	Baseline	Final	Baseline	Final
Echo-Doppler
LVEDV (ml)	79 ± 24	79 ± 20	77 ± 19	79 ± 20	0.71
LVESV (ml)	31 ± 11	31 ± 10	32 ± 14	33 ± 13	0.30
LVSV (ml)	48 ± 13	48 ± 11	46 ± 11	46 ± 10	0.23
LV ejection fraction (%)	61 ± 5	57 ± 8	60 ± 10	55 ± 8	0.12
LV mass	160 ± 36	163 ± 38	150 ± 31	151 ± 33	0.51
LV mass/volume ratio	2.12 ± 0.62	2.13 ± 0.64	2.02 ± 0.46	1.90 ± 0.42	0.64
E wave velocity (cm/s)	79 ± 19	82 ± 19	85 ± 23	88 ± 21	0.61
A wave velocity(cm/s)	93 ± 29	86 ± 29	87 ± 18	84 ± 22	0.61
E deceleration time (ms)	220 ± 55	230 ± 40	227 ± 52	221 ± 52	0.44
E/A ratio	0.90 ± 0.24	1.02 ± 0.28	1.02 ± 0.38	1.12 ± 0.36	0.81
IVRT (ms)	100 ± 20	96 ± 20	92 ± 24	89 ± 18	0.66
Neurohormones
Norepinephrine	307 ± 221	321 ± 290	276 ± 120	360 ± 529	0.71
BNP	45 ± 56	72 ± 115	72 ± 122	55 ± 118	0.06

Data represent means ± SD; p-value represents comparison of least square means at final visit following adjustment for baseline values. Logarithmic transformation was used for the neurohormones, which were non-normally distributed.

Abbreviations: LVEDV: left ventricular end-diastolic volume; LVESV: left ventricular end-systolic volume; LVSV: left ventricular stroke volume; IVRT: isovolumic relaxation time; BNP: brain natriuretic peptide