Table 3.
Multivariate Proportional Hazards Regression Results Within Domains of Predictor Variables
Predictor Domain | Individual Predictor Variablesa | No. of Patients | χ2 Test | P Value |
---|---|---|---|---|
Demographics | Baseline year | 291 | 9.32 | .002 |
Genetic risk | Psychosis in first-degree relatives with functional decline | 291 | 10.37 | .001 |
Positive symptoms | Unusual thought content | 291 | 7.10 | .008 |
Suspicion/paranoia | 291 | 7.97 | .005 | |
Disorganized communication | 291 | 10.97 | <.001 | |
Negative symptoms | Social anhedonia | 287 | 3.24 | .07 |
Reduced ideational richness | 285 | 12.21 | <.001 | |
Disorganization symptoms | Bizarre thinking | 287 | 8.51 | .004 |
Difficulties with concentration | 286 | 3.36 | .07 | |
General symptoms | Reduced tolerance to stress | 286 | 7.92 | .005 |
Functioning | Social function at baseline | 290 | 8.63 | .003 |
General function at baseline | 281 | 5.51 | .02 | |
Decline in role functioning in past year | 290 | 3.51 | .06 | |
Decline in social, role, or psychological functioning in past year | 290 | 4.81 | .03 | |
Drug abuse | Any drug abuse | 270 | 4.99 | .03 |
Antipsychotic drugs | Antipsychotic drugs during follow-up | 287 | 3.71 | .05 |
No variables in the 7 diagnostic comorbidities domain (Table 2) contributed significantly to psychosis risk.