Table 5.
Simplified model for the hazard of cataract types after equating comparable effects; 20,599 participants in the Physicians’ Health Study, 1982–1995
| Cataract Type |
|||
|---|---|---|---|
| Nuclear Sclerotic (1,726 events) | Cortical (734 events) | Posterior Subcapsular (794 events) | |
| HR (95% CI) | HR (95% CI) | HR (95% CI) | |
| BMI, per 1 kg/m2 | 1.03 (1.01–1.05) | 1.00 (0.97–1.03) | 1.06 (1.03–1.08) |
| Multivitamin use | 0.87 (0.78–0.98) | 0.87 (0.78–0.98) | 0.87 (0.78–0.98) |
| Family history of MI | 1.14 (0.98–1.32) | 1.14 (0.98–1.32) | 1.14 (0.98–1.32) |
| Diabetes mellitus | 1.23 (0.96–1.57) | 1.65 (1.19–2.29) | 1.77 (1.29–2.41) |
| Smoke < 1 pack/day | 1.42 (1.11–1.81) | 1.42 (1.11–1.81) | 1.42 (1.11–2.81) |
| Smoke ≥ 1 pack/day | 1.56 (1.29–1.88) | 1.56 (1.29–1.88) | 1.56 (1.29–1.88) |
| Former smoker | 1.14 (1.03–1.26) | 1.14 (1.03–1.26) | 1.14 (1.03–1.26) |
Note: model also allows for different effects of randomized treatment assignment, treats age as the time scale and stratifies on cataract type