Table 1. Heart rate and blood pressure during physical restraint in Wistar rats and SHR.
| Group | Heart rate (1/min) | MAP (mmHg) | |||||
| baseline | stress | relative change (%) | baseline | stress | relative change (%) | ||
| Wistar | vehicle | 372+/−10 | 432+/−8 | 18+/−3 | 90+/−2 | 104+/−1 | 16+/−2 |
| Capadenoson | 374+/−8 | 427+/−5 | 15+/−2 | 100+/−1 | 116+/−2 | 16+/−2 | |
| SHR | vehicle | 324+/−11 | 438+/−7 | 36+/−4 | 164+/−5 | 189+/−3 | 16+/−12 |
| Capadenoson | 328+/−6 | 391+/−8* | 20+/−4* | 175+/−7 | 189+/−6 | 9+/−10 | |
Values are means +/− SEM. n = 20 for Wistar groups, n = 12 for SHR groups. MAP mean arterial pressure.
*p = 0.001 for comparison of the absolute and relative differences of heart rate during restraint stress in capadenoson-treated vs vehicle-treated SHR.