Table 1. Clinical and demographic variables stratified by HIV status.
| HIV-infected(n = 677)Median (IQR)Or n (%) | HIV-uninfected(n = 214)Median (IQR)Or n (%) | p-valueb | |
| Age (years) | 34 (30–39) | 43 (34–50) | <0.01 |
| Self-reported diabetes mellitus | 3 (0.5%)(n = 671)a | 1 (0.5%)(n = 204)a | 1.00 |
| Self-reported hypertension | 32 (4.8%)(n = 671)a | 17 (8.3%)(n = 204)a | 0.06 |
| Weight (kg) | 52 (46–58) | 52 (46–61) | 0.23 |
| Body mass index (kg/m2) | 20.9 (19.0–23.3) | 20.5 (18.5–23.3) | 0.23 |
| Lean body mass (kg) | 40.3 (37.3–42.9)(n = 570)a | 41.4 (38.6–44.7)(n = 204)a | <0.01 |
| Total body fat (kg) | 11.8 (7.8–16.5)(n = 568)a | 10.5 (6.6–18.1)(n = 204)a | 0.47 |
| Systolic blood pressure (mmHg) | 119 (110–122.5) | 120 (110–125)(n = 213)a | 0.019 |
| Diastolic blood pressure (mmHg) | 70 (65–78) | 72 (68.5–80)(n = 212)a | <0.01 |
| CD4 cell count (cells/µl) | 256 (163–360)(n = 675)a | ---- | ---- |
| WHO Stage 4 HIV (with weight loss) | 281 (41.5%) | ---- | ---- |
| Serum albumin (g/dL) | 3.5 (3.1–3.8)(n = 659)a | 4.0 (3.6–4.2)(n = 209)a | <0.01 |
| Serum creatinine (mg/dL) | 0.92 (0.82–1.02)(n = 659)a | 0.85 (0.75–0.96)(n = 206)a | <0.01 |
| eGFR (mL/min/1.73 m2) | 90.0 (78.4–103.9) | 94.5 (82.4–109.3) | <0.01 |
| eGFR<60 mL/min/1.73 m2 | 18 (2.7%) | 3 (1.5%) | 0.44 |
| Proteinuria (urine protein ≥1+) | 55 (9.0%)(n = 614)a | 9 (7.2%)(n = 125)a | 0.60 |
a
For variables with missing data, the number of women with available data is reported.
b
Fisher's Exact test for categorical and Wilcoxon two-sample test for continuous variables.
IQR: interquartile range; WHO, World Health Organization Clinical Stage of HIV; eGFR: estimated glomerular filtration rate by 4-variable Modification of Diet in Renal Disease (MDRD) equation.