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. 2011 Feb 27;5:275–279. doi: 10.2147/OPTH.S10819

Table 2.

RCTs evaluating the visual outcomes or adverse outcomes between antifungal medications

RCT Intervention Number Outcome criteria Outcome
Mahdy 201019 Topical Amphotericin B 0.05% + subconjunctival Fluconazole 0.2% vs Topical Amphotericin 0.05% 48 Number of perforations and visual outcome Both therapies equivalent in both criteria
Prajna 201020 Topical Voriconazole 1% vs Topical Natamycin 5% 120 Visual acuity and number of perforations and corneal transplants Visual acuity slightly superior in Voriconazole but not statistically significant. No difference in rate of complications
Arora 201021 Topical Voriconazole 1% vs Topical Natamycin 5% 30 Visual acuity No significant difference