Table 2.

Treatment details

	Adaptive pacing therapy (n=159)	Cognitive behaviour therapy (n=161)	Graded exercise therapy (n=160)	Specialist medical care alone (n=160)	p value*
Treatment received
Therapy sessions attended†	13 (12–15)	14 (12–15)	13 (12–14)	..	0·17
Specialist medical care sessions attended‡	3 (3–4)	3 (3–4)	3 (3–4)	5 (3–6)	0·0001
Adequate treatment§	143 (90%)	140 (87%)	136 (85%)	142 (89%)	0·56
Antidepressant at baseline	63 (40%)	57 (35%)	74 (46%)	66 (41%)	..
Antidepressant at 24 weeks¶	53 (34%)	45 (29%)	61 (40%)	60 (39%)	0·19
Antidepressant at 52 weeks¶	41 (27%)	47 (31%)	48 (31%)	61 (39%)	0·11
Hypnotic at baseline	6 (4%)	9 (6%)	6 (4%)	5 (3%)	..
Hypnotic at 24 weeks¶	3 (2%)	7 (5%)	5 (3%)	6 (4%)	0·61
Hypnotic at 52 weeks¶	5 (3%)	4 (3%)	3 (2%)	7 (5%)	0·62
Non-allocated treatment	8 (5%)	4 (3%)	7 (4%)	22 (14%)	0·0005
Dropouts from treatment	11 (7%)	17 (11%)	10 (6%)	14 (9%)	0·50
Views before treatment
Treatment is logical	134 (84%)	115 (71%)	135 (84%)	79 (49%)	<0·0001
Confident about treatment	114 (72%)	91 (57%)	112 (70%)	65 (41%)	<0·0001
Views after treatment
Satisfied with treatment¶	128 (85%)	117 (82%)	126 (88%)	76 (50%)	<0·0001
Dissatisfied with treatment¶	4 (3%)	7 (5%)	2 (1%)	17 (11%)	0·0010
Therapeutic alliance‖	6·5 (6·0–6·5)	6·5 (5·5–6·8)	6·5 (5·5–7·0)	..	0·96
Adherence to manual**	6·0 (6·0–6·5)	6·0 (5·0–6·5)	6·5 (6·0–6·5)	..	0·35

Data are median (IQR) or n (%).

^*p values across all groups.

^†86% of sessions were received face-to-face and 14% by telephone.

^‡94% of sessions were received face-to-face and 6% by telephone.

^§Adequate treatment was ten or more sessions of therapy or three or more sessions of specialist medical care alone.

^¶Percentages exclude missing data.

^‖Scored 1–7 (1=poor, 7=excellent).

^**Scored 1–7 (1=not at all, 7=very much so).